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Delaney Laboratory
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April 2012: Craig, Amalia, and Dan defended their PhD work. Congratulations to Dr. Yennie, Dr. Avila Figueroa, and Dr. Jarem!
April 2012: Allison received an NSF Graduate Research Fellowship. Congratulations!
April 2012: Ji successfully defended his Research Proposal Defense. Congratulations!
January 2012: Graduate student A. Muge Bozkurt joins the lab!
January 2012: Dan, Catherine, and Craig published a review in Free Radical Research titled Chemical and Biological Consequences of Oxidatively Damaged Guanine in DNA. [link]
December 2011: Kelly successfully defended her Original Research Proposal and Ji completed cumes! Great work!
December 2011: Catherine and Dan have their work on the ability of trinucleotide repeat DNA to accomodate the 8-oxo-7,8-dihydroguanine lesion accepted for publication in Biochemistry. Congratulations! [link]
November 2011: Dan's manuscript 'Premutation huntingtin allele adopts a non-B conformation and contains a hot spot for DNA damage' is published in Biochemical and Biophysical Research Communications. Great work! [link]
September 2011: Kelly received a Best Poster Award at the annual departmental poster session. Congratulations!
Archive of past group news
Research in the Delaney laboratory aims to understand the biological consequences of DNA damage. Using the methods and tools of biochemistry, biophysics, synthetic chemistry, molecular biology, and toxicology we probe the effects of DNA damage from the molecular to the cellular level. We exploit our abilities to synthesize modified DNA nucleobases and study their properties within well-defined systems. We are particularly interested in oxidative DNA damage and its contributions to cancer and neurological disorders such as Huntington’s disease.